Clonidine hydrochloride in the treatment of hypertension

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چکیده

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Clonidine hydrochloride in the treatment of hypertension.

From the Hypertension Section, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich. This study was assisted by U. S. Public Health Service Grant 5MOl-FR-42 to the Clinical Research Unit, University of Michigan Medical Center, which enabled hospitalization of patients included in the study. Manuscript received December 14, 1970, accepted February 12, 1970. Add...

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Validated Colorimetric Assay of Clonidine Hydrochloride from Pharmaceutical Preparations

Clonidine hydrochloride is an antihypertensive agent used for migraine prophylaxis, attention deficit hyperactivity disorder, menopausal flushing and Tourette syndrome. The quantity of the active substance in pharmaceutical preparations must be within specific limits, in agreement with the respective label claim. Therefore, the aim of this study was to establish the conditions for two spectroph...

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Clonidine monotherapy in mild hypertension.

In our study of adolescents with sustained hypertension, single-agent therapy with clonidine significantly reduced blood pressure and heart rate, while hydrochlorothiazide as a single agent significantly reduced only systolic pressure. After 24 weeks of therapy, 40 percent of the diuretic-treated group achieved the treatment goals vs 87 percent in the group treated with clonidine. No alteration...

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ژورنال

عنوان ژورنال: The American Journal of Cardiology

سال: 1971

ISSN: 0002-9149

DOI: 10.1016/0002-9149(71)90036-1